Ionizing radiation-induced metabolic oxidative stress and prolonged cell injury
نویسندگان
چکیده
منابع مشابه
Ionizing Radiation-Induced Oxidative Stress Alters miRNA Expression
BACKGROUND MicroRNAs (miRNAs) are small, highly conserved, non-coding RNA that alter protein expression and regulate multiple intracellular processes, including those involved in the response to cellular stress. Alterations in miRNA expression may occur following exposure to several stress-inducing anticancer agents including ionizing radiation, etoposide, and hydrogen peroxide (H(2)O(2)). ME...
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Exposure of cells to gamma-rays induces the production of reactive oxygen species (ROS) that play a main role in ionizing radiation damage. We have investigated the radioprotective effect of phloroglucinol (1,3,5-trihydroxybenzene), phlorotannin compound isolated from Ecklonia cava, against gamma-ray radiation-induced oxidative damage in vitro and in vivo. Phloroglucinol significantly decreased...
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ژورنال
عنوان ژورنال: Cancer Letters
سال: 2012
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2011.12.012